We present an overview of cross-section measurements at BABAR. In e+/- to few-body processes at a center-of-mass energy E{CM} = 10.6 GeV we make new QCD tests and the first observation of two-virtual-photon annihilations into hadrons. Studies at lower sqrt s, using radiative return, yield new/improved data on spectroscopy, form factors and the total hadronic cross section, an important input to calculations of gmu-2 and alpha(MZ). We also present an inclusive measurement of the running of alpha.